African Spiny Mice Can Regrow Skin: A Model for Human Wound Healing
Can humans someday regenerate like the superhero Deadpool? Studies on tissue restoration in African spiny mice reveal the potential genetic origin for this extraordinary occurrence. With continued research in wound healing, the unappealing scars humans are subjected to may someday be replaced by rejuvenated skin. Check out the story for more details!
Ushering in Gene Therapy for Usher Syndrome Patients
Scientists from Boston Children’s Hospital are investigating a gene therapy treatment to treat Usher syndrome, a genetic condition that causes deafness and blindness.
Looking at Armadillos for a Cure to Blindness
Normally when studying disorders that cause blindness in humans, scientists genetically disable cone-related genes in small animals like mice. Studying nine-banded armadillos would give scientists a much more realistic model to test viable treatment options, such as gene therapy, a method of correcting a genetic disease by replacing defective genes with corrected copies. If gene therapy were able to correct the nine-banded armadillo’s cone-related mutations, it could be adapted to correct forms of human blindness.
Finding Hope in the Dark: Appaloosas Shining a Light on Human Night Blindness
Scientists found that people who have night blindness also have proteins that do not function properly, and fail to send electrical images from the rods to the brain. This connection between night blindness in horses and humans gives us the opportunity to further investigate the cause of CSNB and how we can treat it in both humans and animals.
Kitties & Kids: Fighting a Fatal Genetic Disease
Now that Siamese cats are available as genetic models for Niemann-Pick disease, in-depth studies on the biochemical properties of the disease are being performed. Previously, studies on Niemann-Pick disease were performed on rodents with drug-induced enzyme deficiencies, which was less than ideal. Although there are obstacles to be faced, researchers are optimistic that Siamese cats will speed the search for a cure or effective treatments for Niemann-Pick disease.
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